Compounds in development act on targets like fatty acid synthase and carnitine palmitoyl transferase FASgen is studying the effects of inhibition of the fatty acid biosynthesis pathway on the regulation of appetite and weight loss. The firm has developed various families of compounds that act on well-identified targets in the pathway, including fatty acid synthase FAS , carnitine palmitoyl transferase-1 CPT-1 , and mitochondrial glyceraol-3aclytransferase GPAT. The research is partly conducted in cooperation with labs at Johns Hopkins University.
Method of neuroprotection by pharmacological inhibition of AMP-activated protein kinase. Patent number: Abstract: A method of neuroprotection which comprises administration of an AMPK inhibitor to a patient who is experiencing or has experienced a stroke, the compound being an AMPK inhibitor. Treatments with these agents significantly reduce the size of infarcts, and therefore minimize the loss of brain tissue and neurons. Thus, function can be preserved after stroke or ischemic injury in the brain. Similarly, neuronal loss can be minimized in degenerative diseases that cause neuronal compromise by perturbing energy utilization and availability in neurons. Type: Grant. Filed: March 23, Date of Patent: October 23,
I think about leaving all the time now because by myself there are no disappointments. Through this, if you run into unforeseen issues like sold out movies or you cannot get a seat at a restaurant, you will always have a backup plan. That said, I like to hope that love can be more powerful than belief. Notify me of new comments via email. If she says yes. Reading your messages I don't feel bad about being in the shadow of his career. And he is reading one of my favorite Buddhist-based books, in an effort to understand my beliefs. These are nice people.